SOCS3 anticorps

N° du produit ABIN207073

Cet anticorps Souris Monoclonal détecte spécifiquement SOCS3 dans WB et Inhibition. Il présente une réactivité envers Humain.

Aperçu rapide pour SOCS3 anticorps (ABIN207073)

Antigène: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOCS3 est non-conjugé

Application: Western Blotting (WB), Blocking Antibody (Inhibition)

Clone: SO1

Détail du produit anti-SOCS3 anticorps

Specificité: The cytokine signaling is known to be regulated by a negative feedback regulator called suppressor of cytokine signaling (SOCS) inhibitors family. Members of the SOCS family have been identified due to their marked homology on the SH2 domain and a unique conserved motif referred to as the SOCS box. Expression of SOCS3 is transiently induced in a variety of immune and inflammatory situations by a wide variety of cytokines. SOCS3 is also involved in growth hormone function, leptin and insulin signaling. SOCS3 inhibits Janus kinase (JAK) tyrosine kinase activity

Purification: Protein A purified

Immunogène: Full-length SOCS3 protein.

Type of Immunogen: Recombinant protein

Isotype: IgG2b

Information d'application

Indications d'application: Approved: Inhb, WB

Usage: Western Blotting: Positive control - HeLa human cervix carcinoma cell line. Sample preparation: Resuspend approx. 50 mil. cells in 1 mL cold Lysis buffer (1 % laurylmaltoside in 20 mM Tris/Cl, 100 mM NaCl  pH 8.2, 50 mM NaF including Protease inhibitor Cock

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Détails sur SOCS3

Antigène: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Autre désignation: SOCS3

Sujet: Name/Gene ID: SOCS3

Synonyms: SOCS3, Cish3, Cytokine-induced SH2 protein 3, CIS-3, CIS3, SSI-3, STAT-induced STAT inhibitor 3, SSI3, ATOD4, SOCS-3

ID gène: 9021

UniProt: O14543

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus, Hepatitis C